10 Best Piroctone Olamine Shampoos for Treating Seb Derm & Dry Scalp

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Dandruff is a common condition that causes dry, flaky skin on the scalp. It can also cause itching and redness. For some people, dandruff may be caused by an overgrowth of yeast in the scalp called Malassezia furfur (also known as pityrosporum).

While there are different solutions for dandruff, one of the most effective solutions is using piroctone olamine shampoos. For those who don’t know, Piroctone Olamine is a kind of therapeutic shampoo that is used for treating Seb derm and dry scalp. It also assists in minimizing hair shedding, improving the appearance of hair, and reducing dandruff.

Piroctone olamine works by lowering the levels of lipids on the surface of your scalp which is responsible for making skin cells grow more rapidly than they should. Since there are hundreds of different brands that makes piroctone olamine shampoos, finding the right one for you need might be super challenging.

So, to help you find the best piroctone olamine shampoos, we’ve done all the research and hard works and combined here a list of the best shampoos with piroctone olamine. Just read it out and choose the one that fits your need!

Complete List of Best Piroctone Olamine Shampoos

What Is Piroctone Olamine?

Piroctone olamine is a chemical compound that was first developed by the Japanese company Kao Corporation. It is derived from ethanolamine salt extracted from hydroxamic acid piroctone. [1]

In instances where a commonly used compound, zinc pyrithione, is not an option for someone with hair loss or a dry scalp, Piroctone Olamine may be an alternative treatment.

The goal was to create an active ingredient for use in shampoos and other personal care products, which would help treat seborrheic dermatitis and dry scalp conditions. It’s used in shampoos and other personal care products to help treat seborrheic dermatitis, dandruff, itchy scalp conditions, and dry skin.

Since millions of people has some hair problem such as dandruff, hair loss, slow hair growth, or split ends. Usage of shampoo containing piroctone olamine can help in solving these problems for the user.

How Does Piroctone Olamine Work?

As mentioned above, Piroctone olamine is a salt of piroctone, with complex anti-fungal properties. Evidence suggests that it works as well as ketoconazole shampoos on patients with scalp seborrhea, dandruff, and other fungal infections on the skin or hair caused by Malassezia fungi.

Piroctone olamine is an anti-inflammatory. It blocks the production of a substance called leukotriene B(LTB), which leads to inflammation and scaling on your skin. The fungus found on one’s scalp is natural, but some people are sensitive and react alarmingly to the chemicals it produces. 

Piroctone olamine stops the process when skin becomes irritated and the body reacts by rapidly shedding skin to get rid of the irritant, causing flaking. Stopping this process is key to stop dandruff or any type of itchiness.

How Effective Is Piroctone Olamine?

Piroctone olamine is very effective at treating seborrheic dermatitis, dandruff, itch scalp conditions, and dry skin but not as much to treat psoriasis or eczema because the latter two can make those conditions worse.

In clinical studies conducted on human subjects suffering from seborrheic dermatitis showed improvements in symptoms after using piroctone olamine shampoos for only one month up to three months.

You may see great benefits from Piroctone Olamine if you have seborrheic dermatitis, dandruff or itch scalp conditions, and dry skin but not as much with psoriasis or eczema which can make those conditions worse. Using Piroctone Olamine shampoos on your hair for a duration of one month to three months will show improvements in acne-prone skin.

Risks or side effects of Piroctone Olamine

There are no known risks associated with this chemical component. However, there have been some reports linking exposure to piroctone olamine in shampoos with skin reactivity problems such as eczema, especially among children who

As you know, piroctone olamine is an ingredient found in many shampoos that helps with dry skin and itchy scalp conditions. It blocks the production of a substance called leukotriene B(LTB), which leads to inflammation and scaling on your skin.

1. Alpecin Dandruff Killer Shampoo

Alpecin Dandruff Killer Shampoo is formulated with piroctone olamine to kill the bacteria that causes dandruff. 

The shampoo is made of herbal extracts and has a low pH in its formula, which can help control itchiness, flaking, or dryness on your scalp without drying out your hair’s natural oils. It also contains natural ingredients like caffeine from coffee beans to stimulate circulation and promote healthy skin cells. 

Alpecin Dandruff Killer Shampoo contains 1% pyrithione zinc to help prevent the flaking and itching associated with dandruff. Zinc pyrithione also helps in protecting against oil buildup and controls the growth of yeast on your skin’s surface.  It features a soothing botanical blend for itchy scalp conditions, dandruff, or seborrheic dermatitis.

Overall, it is gentle enough for daily use but highly effective when combined with other treatments like antihistamines to reduce symptoms associated with psoriasis, eczema, asthma, and more. For best results, shake well before use, and use at least twice a week or as directed by a doctor.

2. Body Shop Ginger Scalp Care Shampoo

Body Shop Ginger Scalp Care Shampoo is Blended with potent ginger, its iconic scalp care conditioner that moisturizes the scalp and leaves hair feeling soft.  This shampoo is used for dry flaky scalps helps to remove loose flakes and soothes the scalp.

It is a pH-balanced shampoo that gently cleanses the scalp, and removes excess oils. It contains no harsh chemicals or animal-derived ingredients and is suitable for all hair types.

Body shop ginger shampoo is Sulfate-free so it won’t strip your hair of its natural lipids that can result in dryness, brittleness, and breakage. This gentle cleansing formula leaves you feeling refreshed without stripping moisture from your skin leaving it soft & supple.

We recommend using this shampoo as part of the routine for healthy-looking hair. For best results, use twice a week with Body Shop Ginger Scalp Care Conditioner to maintain healthy shiny hair.

3. Philip Kingsley Flaky Scalp Cleansing Shampoo

Philip Kingsley Flaky Scalp Cleansing Shampoo is a gentle, soothing shampoo that helps clear scalps of stubborn flakes and skin-cell build-up.

This is a great product if you have a dry or itchy scalp. It’s extremely soothing with fresh apple fragrance, moisturizes, and relieves irritation while clearing flakiness and oil build-up from your hair.

The shampoo contains piroctone olamine, which is an anti-fungal that helps to clear the scalp of flakes and soothe irritation. It also contains lauryl betaine which cleanses your hair without redness or irritation, as well as soothing ingredients such as chamomile and aloe vera.

Try to apply it on wet hair and gently kneading the scalp for 60 seconds. Rinse well, repeat if necessary. Won’t dry out your hair or strip it of color. 

Overall, not only does it cleanse, but it also moisturizes and relieves irritation. I would recommend this product for people who want to get rid of flakes.

4. Sebamed Scalp Balancing Shampoo

Sebamed’s Scalp Balancing Shampoo is one of the best anti-fungal shampoos for seb derm, with a unique formula that leaves your scalp feeling fresh and clean. It is free from harsh detergents or perfumes which can be irritating to sensitive scalps like yours. 

The shampoo contains zinc pyrithione as its active ingredient––a powerful natural antifungal agent that helps to prevent dandruff outbreaks by stopping fungi before they spread on the skin’s surface.

Sebamed shampoo contains an active ingredient, salicylic acid, which helps to reduce dandruff and the resulting flaking. This gentle anti-dandruff shampoo contains natural ingredients that are kind to your hair as well as your scalp. 

Sebamed’s Scalp Balancing Shampoo is clinically proven to reduce itching and irritation on the scalp, remove visible signs of dandruff after just 14 days and restore a healthy shine to hair. The clinically proven formula of this anti-dandruff shampoo also contains soothing ingredients such as panthenol (provitamin B5) and allantoin to care for your scalp.

Overall, not only does it reduce the occurrence of dandruff, but it also helps to provide relief for dry and itching scalp. If you have a problem with dry scalp, this is the best shampoo for you.

5. Sebclair Shampoo

Sebclair Biotin shampoo is a mild, SLS-free formula that gently cleanses and prevents hair loss. It contains biotin, which is an essential vitamin for healthy hair growth.

It also contains olive oil which leaves your scalp moisturized, preventing it from drying out. The shampoo also includes natural extracts to protect the scalp and nourish the hair from root to tip for healthier hair growth. 

This product is safe for color-treated or chemically processed hair as well as extensions, wigs, and weaves. The main ingredient, sodium chloride (salt), will strip out the keratin in your hair and give you a fresh start. 

This shampoo can be used daily or as often as needed to remove build-up from styling products like gels/pomades/waxes/sprays etc.

Overall, not only does Sebclair Shampoo work to get rid of seborrheic dermatitis and dry scalp, but it also helps improve hair strength and reduce shedding. Sebclair Shampoo is a product you can trust when looking for relief from the discomfort that comes with having seborrheic dermatitis or an irritated, flaky scalp.

6. Sebclair Dermatola Cream

Well, this one is different from other but effective like most of the products in this list. Sebclair cream is a product designed for the treatment of seborrheic dermatitis. 

It’s completely natural and organic safe to use as a face cream for treating Seborrheic Dermatitis. It uses non-steroidal anti-inflammatory and anti-fungal properties to treat inflammation, scaling, and itching of this condition.

Sebclair is a cream that should only be applied to the affected area so it doesn’t cause any irritation or unwanted reactions. It’s made with all-natural ingredients too.  It’s dermatologist tested and free of parabens, fragrance, and sulfates. It can also be used for other skin conditions like eczema and psoriasis as well.[2]

This product may take up to 10 days before you notice some relief but it’s worth it in the end when your seborrheic dermatitis will clear up completely without causing further damage to the hair follicles or scalp tissue which would lead to hair loss.

Overall, it also starts to heal the skin that was previously affected by this condition.

7. SACHAJUAN Normalizing Shampoo

SACHAJUAN Normalizing Shampoo is a gentle cleansing shampoo with Ocean Silk Technology, Climbazole, and Piroctone Olamine to maintain a healthy scalp and hair.

It adds volume and bounce, with a refreshing effect. Massage a small amount into wet hair. Rinse thoroughly. Lathers well and rinses clean without leaving any residue.

This shampoo is gentle enough to be used every day, this product is also safe on color-treated hair. 

It won’t strip your hair of natural oils or dry out the scalp like some other shampoos might do when you need to wash daily due to certain circumstances (like sweating heavily).

If you have sensitive skin and are looking for an all-natural shampoo that is gentle enough to use every day (even when your hair needs more frequent washing), then SACHAJUAN Normalizing Shampoo could be a good choice.

8. As I Am Dry & Itchy Scalp Care Shampoo

As I am Dry & Itchy Scalp Care Shampoo is a sulfate-free shampoo that helps to relieve scalp itch, flaking, dryness, redness, and irritation associated with seborrheic dermatitis and dandruff.

This botanical-based formula cleanses and moisturizes your scalp leaving your curls refreshed without stripping your hair of its natural oils. 

The shampoo is infused with Zinc Pyrithione 1%, an active ingredient known for its effectiveness. This Shampoo is a completely natural and organic shampoo. It has been specially formulated to help with dry scalp and itchy hair. 

The shampoo is packed full of ingredients used for generations to soothe the skin and nourish the hair, such as tea tree oil, peppermint oil, olive oil, and linseed extract.

These ingredients have been blended with more modern ingredients like aloe vera juice and disodium laureth sulfosuccinate to create a gentle but effective cleanser that helps relieve dry scalp problems.

This lathering cleanser cleanses your hair while moisturizing your hair and scalp leaving it refreshed.  The pH-balanced formula gently removes product build-up and environmental impurities from the hair and scalp as it provides relief from the discomfort associated with seborrheic dermatitis.

Overall,  this shampoo is designed to be gentle, yet effective and it does a great job at doing just that. I recommend this shampoo to anyone who wants a gentle shampoo that feels refreshing and cleanses the scalp without stripping it of essential oils.

9. RAUSCH Coltsfoot Anti-Dandruff Shampoo

RAUSCH Coltsfoot Anti-Dandruff Shampoo is a mild and gentle shampoo that cleanses the scalp gently. The herbal active complex of coltsfoot and burdock root extract as well as piroctone olamine soothes itching and redness, relieves dandruff, and prevents it from coming back.

No silicones or parabens are used in this natural product. The shampoo is gentle to the scalp, non-irritating, dermatologically tested and free from silicones and parabens.

A blend of natural ingredients including tea tree oil, olive oil, peppermint oil, and linseed extract helps keep your scalp nourished, hydrated and healthy. Our 100% plant-based shampoo is infused with essential oils to help strengthen hair follicles and prevent dryness.

Overall, not only does it help prevent future outbreaks of seb derm, but it also helps with the itching and discomfort that’s associated with this common skin condition.

10. Topicrem PV Cleansing Gel

Topicrem is a unique dermo-cosmetic product for the body, scalp, and external intimate area. It gently cleanses, leaves the skin hydrated, respects soothes, and protects (the external intimate area).

It contains natural ingredients that purify and cleanse the skin without dehydrating it.  Its formula with 10% of zinc oxide protects against external aggressions (pollution, sun) while respecting the skin’s natural balance. The ingredients in this product work together to provide you with optimal results.

Topicrem has a light texture that makes it easy to remove dandruff and dead skin cells from the scalp or your feet. Its neutral pH leaves no greasy film on your skin or hair. 

Topicrem purifies your skin by removing impurities from the surface of your skin as well as any dandruff or flaking that may be present. This product was created to help with these problems by establishing and maintaining the lipid balance in the scalp layer of the skin.

Overall,  this is one of the best piroctone olamine shampoos for treating seb derm and dry scalp that you can find. If you are looking for a shampoo to help with dry scalp or dandruff, my highly recommended is Topicrem.


Overall all the products are benefited but I must recommend you to see what is suitable for you.  As per my personal preference, I highly recommend As I Am Dry & Itchy Scalp Care Shampoo product because it is the best solution to treat seb derm and dry scalp. 

It has 10% of piroctone olamine formula with other 10 key ingredients that can easily make you free from problems like dandruff, itchy, flaky, redness, or any kind of irritation on your scalp. 

This product is highly recommended by dermatologist Dr. Jeanette Graf and she also suggests this product for her patients who suffered a severe seborrheic dermatitis problem.

Frequently Asked Questions

1. Is Piroctone Olamine natural?

No, Piroctone Olamine is a petrochemical with an origin similar to ethanolamine, and it is extracted from hydroxamic acid. Piroctone Olamine typically serves as an alternative to the commonly used zinc pyrithione compound when there are allergic reactions. There are no natural alternatives that come anywhere close to being as effective.

2. Does Piroctone Olamine cause hair loss?

No, Scratching the scalp can damage hair and may cause hair loss other than this there is no chance of hair loss with the use of Piroctone Olamine.

Hair loss is closely associated with seborrheic dermatitis because increased sebum production can create irritation and inflammation on the scalp, which can cause intense itchiness.

3. Is Piroctone Olamine organic or inorganic?

Piroctone Olamine starts as an organic compound but then gets processed into the synthetic version that we know today through a process known as ethoxylation.

The processing removes all traces of hydroxamic acid and converts it to its petrochemical alternative-hydroxy ethoxy ethyl amide which has virtually zero antifungal properties.

This means that our skin can never benefit from any trace levels of organic compounds like hydroxamic acid after they have been mixed with these hydrocarbons.

4. Is Piroctone Olamine antifungal?

Piroctone olamine is not an antifungal but rather, a sebostatic. This means that it stops the overproduction of oil which in turn soothes inflammation and itchiness associated with skin conditions like psoriasis, eczema, acne rosacea, or seborrheic dermatitis.

In addition to its antifungal activity, piroctone olamine also has good bacterial antibacterial properties.

5. Is Piroctone Olamine better than zinc pyrithione?

The efficacy of piroctone olamine in the treatment of seborrheic dermatitis has been evaluated by only a few studies and these have yielded mixed results. One study found it to be more effective than coal tar or sulfur, whereas another showed no difference from placebo.

More research is needed before conclusions can be drawn about its effectiveness for this indication as compared with other treatments like Zinc Pyrithione which are widely used at present.

6. How do you dissolve Piroctone Olamine?

Piroctone-Olamine (also known as ciclopirox) cannot typically be dissolved in water but is soluble in ethanol or acetone.

7. Does “Head and shoulders” have Piroctone Olamine?

The Head & Shoulders shampoo does not contain the ingredient piroctone olamine, but it is a common inactive ingredient that helps with the foamability of the product and prevents mold from forming on its surface.

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